Zeliang Wei Selected Research

Diosgenin

6/2022	Drug D, a Diosgenin Derive, Inhibits L-Arginine-Induced Acute Pancreatitis through Meditating GSDMD in the Endoplasmic Reticulum via the TXNIP/HIF-1α Pathway.
1/2020	A pH-Sensitive Prodrug Nanocarrier Based on Diosgenin for Doxorubicin Delivery to Efficiently Inhibit Tumor Metastasis.
1/2018	Dihydrodiosgenin protects against experimental acute pancreatitis and associated lung injury through mitochondrial protection and PI3Kγ/Akt inhibition.
1/2018	The diosgenin prodrug nanoparticles with pH-responsive as a drug delivery system uniquely prevents thrombosis without increased bleeding risk.
9/2016	Corrigendum to "Preventive effect of a novel diosgenin derivative on arterial and venous thrombosis in vivo" [Bioorg. Med. Chem. Lett. 26 (2016) 3364-3369].
1/2016	Preventive effect of a novel diosgenin derivative on arterial and venous thrombosis in vivo.

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Zeliang Wei Research Topics

Disease

9	Thrombosis (Thrombus) 01/2022 - 01/2016
5	Mitochondrial Diseases (Mitochondrial Disease) 01/2022 - 01/2017
5	Neoplasms (Cancer) 01/2020 - 10/2015
4	Inflammation (Inflammations) 06/2022 - 01/2020
4	Pancreatitis 06/2022 - 01/2020
4	Necrosis 06/2022 - 01/2018
4	Hemorrhage 01/2022 - 01/2016
3	Neoplasm Metastasis (Metastasis) 01/2020 - 09/2017
2	Macular Degeneration (Age-Related Maculopathy) 09/2022 - 12/2020
2	Blindness (Hysterical Blindness) 09/2022 - 12/2020
2	Type 2 Diabetes Mellitus (MODY) 08/2020 - 11/2016
2	Melanoma (Melanoma, Malignant) 01/2020 - 01/2017
2	Venous Thrombosis (Deep-Vein Thrombosis) 09/2016 - 01/2016
1	Obesity 09/2022
1	Acute Necrotizing Pancreatitis 06/2022
1	Hypertension (High Blood Pressure) 12/2021
1	Homocystinuria 01/2021
1	Ischemic Stroke 08/2020
1	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 08/2020
1	Cerebral Infarction 08/2020
1	Hypoglycemia (Reactive Hypoglycemia) 08/2020
1	Stroke (Strokes) 08/2020
1	Edema (Dropsy) 01/2020
1	Esophageal Neoplasms (Esophageal Cancer) 01/2020
1	Hepatitis 01/2020
1	Adenocarcinoma 01/2020
1	Esophageal Squamous Cell Carcinoma 01/2020
1	Skin Neoplasms (Skin Cancer) 01/2020
1	Digestive System Diseases 01/2020
1	Hepatocellular Carcinoma (Hepatoma) 01/2019
1	Cataract (Cataracts) 06/2018
1	Ulcer 01/2018
1	Carotid Artery Injuries 01/2017
1	Thrombocytopenia (Thrombopenia) 01/2016
1	Experimental Melanoma 10/2015
1	Body Weight (Weight, Body) 10/2015

Drug/Important Bio-Agent (IBA)

6	DiosgeninIBA 06/2022 - 01/2016
5	Pharmaceutical PreparationsIBA 06/2022 - 05/2014
4	Reactive Oxygen Species (Oxygen Radicals)IBA 09/2022 - 01/2017
3	ProdrugsIBA 01/2020 - 09/2017
2	IntegrinsIBA 01/2022 - 01/2022
2	Adenosine Triphosphate (ATP)IBA 01/2022 - 06/2018
2	Sirtuin 1IBA 01/2021 - 01/2017
2	Metformin (Glucophage)FDA LinkGeneric 08/2020 - 11/2016
2	Taurocholic Acid (Sodium Taurocholate)IBA 01/2020 - 01/2018
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2020 - 09/2017
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2018 - 01/2016
2	Mitochondrial DNA (mtDNA)IBA 01/2017 - 11/2016
2	ferric chlorideIBA 01/2017 - 01/2016
1	BerberineIBA 09/2022
1	Arginine (L-Arginine)FDA Link 06/2022
1	Neuropilin-1IBA 01/2022
1	Caspase 3 (Caspase-3)IBA 01/2022
1	TuftsinIBA 01/2022
1	CalciumIBA 12/2021
1	Grammostola spatulata MTx4 proteinIBA 12/2021
1	Polysaccharides (Glycans)IBA 07/2021
1	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 01/2021
1	Glutathione (Reduced Glutathione)IBA 01/2021
1	Biological ProductsIBA 12/2020
1	Ophthalmic Solutions (Eye Drops)IBA 12/2020
1	Purinergic P2X7 ReceptorsIBA 09/2020
1	entecavir FDA Link 09/2020
1	BiguanidesIBA 08/2020
1	Dehydrocholic Acid (Sodium Dehydrocholate)IBA 01/2020
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2020
1	Cytochrome P-450 CYP1A1 (CYP1A1)IBA 01/2020
1	PolymersIBA 01/2020
1	Epidermal Growth Factor (EGF)IBA 01/2020
1	Bile Acids and Salts (Bile Acids)IBA 01/2020
1	N-acetyltalosaminuronic acid (NAT)IBA 01/2020
1	TrypsinIBA 01/2020
1	Therapeutic UsesIBA 01/2020
1	Amylases FDA Link 01/2020
1	Lipase (Acid Lipase)FDA Link 01/2020
1	Blood Coagulation Factors (Coagulation Factor)IBA 01/2019
1	Factor VIII (Coagulation Factor VIII)IBA 01/2019
1	Cadherins (E-Cadherin)IBA 01/2019
1	Matrix Metalloproteinases (MMPs)IBA 06/2018
1	SugarsIBA 06/2018
1	Galactose (Galactopyranose)FDA LinkGeneric 06/2018
1	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 06/2018
1	EstersIBA 01/2018
1	Fibrinolytic Agents (Antithrombotic Agents)IBA 01/2018
1	MicellesIBA 01/2018
1	palmitoleic acidIBA 01/2018
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 09/2017
1	Ibuprofen (Motrin)FDA LinkGeneric 09/2017
1	Drug CarriersIBA 09/2017
1	Antineoplastic Agents (Antineoplastics)IBA 06/2017
1	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 01/2017
1	xanthohumolIBA 01/2017
1	deoxyarbutinIBA 01/2017
1	Eosine Yellowish-(YS) (Eosin)IBA 10/2015
1	Hematoxylin (Haematoxylon)IBA 10/2015
1	SaponinsIBA 10/2015

Therapy/Procedure

5	Therapeutics 12/2020 - 01/2016
1	Oral Medicine 08/2020
1	Drug Therapy (Chemotherapy) 09/2017
1	Ligation 01/2017